Description
A Year with Oxystim
LIQUID OXYGEN CULTURE™ – Complex natural B15 pangamic acid rich culture
Vitamin B15 (dimethylglycine, pangamic acid, calcium pangamate) is a water soluble substance. B15 is a coenzyme that catalizes chemical reactions and biological processes involved in energy production and nervous system functioning. It has been promoted as a supplement for a variety of health conditions, including alcoholism, asthma, and heart disease, including immune system support, athletic performance, and cancer prevention.
ATHLETIC PERFORMANCE
Effect of pangamic acid and the combination of calcium gluconate with glycine on the biochemical changes in blood of athletes performing physical exercises.
Pangamate helped stabilize sugar, lactic acid, glutathione fractions in blood speeded up return to biochemical normal during the rest period.
BEHAVIOURAL DISTURBANCES
Neuroscience experts found B15 protective against behavioural disturbances and synaptic deficits. Memory impairments and psychiatric effects induced by repeated ketamine exposure. Repeated ketamine exposure attenuated synaptic transmission and plasticity. Dimethylglycine prevented ketamine-induced behavioral and synaptic deficits. (2021 article)
NERVE INJURY REPAIR
B15 shown a promoting effect on the regenerative ability post injury on basal root ganglion neuronal axion. Researchers further suggest B15 may be a candidate drug to repair nerve injury. (2022 article)
IMMUNOMODULATORY
Patients were injected with pneumococcal vaccine and there was a 4 fold increase in antibody production among those who orally took B15 compared to placebo group.
In vitro response from patients suffering from diabetes and sickle sickle cell disease shown 3 fold increase in lymphocite response with B15 addition to mitotic stimulators compared to stimulators alone.
ANTI-MUTAGENIC – Protects against genetic damage
Pangamic acid shown anti-mutagenic activities caused by sodium azide induced genetic damage then measured by Ames Salmonella/microsome mutagenicity assay. Ames Salmonella is a short-term bacterial reverse mutation assay specifically designed to detect a wide range of chemical substances that can produce genetic damage that leads to gene mutations.
Karpuhina, J. L., Orescenko, N. I., & Stoljarova, N. A. (1967). Effect of pangamic acid, methionine, and the combination of calcium gluconate with glycine on the biochemical changes in blood of athletes performing physical exercises. Voprosy Pitaniya, 26(1), 3-6. https://www.cabdirect.org/cabdirect/abstract/19671406915
Greene, H. M., Wickler, S. J., Bray, R. E., Burrill, M. J., & London, C. (1996). The effect of N, N-dimethylglycine on athletic performance at altitude in horses and mules. Pferdeheilkunde, 12(4), 499-501. DOI: 10.21836/PEM19960430
Charles D. Graber, Jean M. Goust, Armand D. Glassman, Roger Kendall, C. Boyd Loadholt, Immunomodulating Properties of Dimethylglycine in Humans, The Journal of Infectious Diseases, Volume 143, Issue 1, January 1981, Pages 101–105, https://doi.org/10.1093/infdis/143.1.101
Chung-Pin Hsieh, Shao-Tsu Chen, Mei-Yi Lee, Chieh-Min Huang, Hwei-Hsien Chen, Ming-Huan Chan, N, N-dimethylglycine Protects Behavioral Disturbances and Synaptic Deficits Induced by Repeated Ketamine Exposure in Mice, Neuroscience, Volume 472, 2021, Pages 128-137, ISSN 0306-4522, https://doi.org/10.1016/j.neuroscience.2021.08.004.
Plucar, B., Nepovimova, E., Valis, M., & Kuca, K. Millennium Nutrient N, N-Dimethylglycine (DMG) and its Effectiveness in Autism Spectrum Disorders. https://doi.org/10.2174/0929867328666211125091811
STUDIES IN MUTAGENESIS AND ANTI-MUTAGENESIS. I. ANALYSIS OF CHROMIUM, SELENIUM, VITAMIN B-15 (PANGAMIC ACID), AND GINSENG (PANAX)JANIS FEGLEY, LAURA FEDAK and LESTER J. TUROCZI Proceedings of the Pennsylvania Academy of Science Vol. 57, No. 2 (1983), pp. 181-184 (4 pages)Published By: Penn State University Press https://www.jstor.org/stable/44111468
Kato, Y., Kuwabara, H., Okada, T. et al. Oxytocin-induced increase in N,N-dimethylglycine and time course of changes in oxytocin efficacy for autism social core symptoms. Molecular Autism 12, 15 (2021). https://doi.org/10.1186/s13229-021-00423-z
MULTIENZYME COMPLEX BEE POLLEN™ – Bee pollen further enhanced with enzymes and nutrients
MUSCLE MASS, PSYSICAL STRESS
2021 Research conducted in Japan results showed that physical stress and muscle mass were significantly improved in the Bee Pollen group compared with the placebo group.
INCREASED MUSCULAR STRENGTH AND SWIMMING TIME
Bee pollen increased muscular strength and swimming time after taking the pollen for swimming athletes compared to placebo group
Sugiura, S. I., Kanaiwa, M., Nakatani, Y., Nishimura, M., Sugisawa, M., Tsuneoka, R., … & Nakanishi, H. (2021). Effects of bee pollen on athletes’ conditions and exercise performances. Glycative Stress Research, 8(1), 45-61. https://doi.org/10.24659/gsr.8.1_45
Chen, H., Wang, S., & Liu, Y. (1986). “Study Of The Effect Of Bee-Pollen On Improving Sport Performance”, Chinese Journal Of Sports Medicine. Beijing, Vol. 5 (2), 69- 74;126. https://pesquisa.bvsalud.org/portal/resource/pt/wpr-581379
ZINC ASPARTATE
Zinc Aspartate alleviates lung injury induced by Intestinal Ischemia-Reperfusion that is attributable to its antioxidant and antiinflammatory effects.
Zinc aspartate shown protective against lethal dose of ionizing gamma radiation against mice where treated mice 80-90% survived. Radioprotector zinc aspartate selectively protected bone marrow against radiotherapy induced gamma radiation, while did not inhibit the radiation effects against the tumor. Experts say that zinc aspartate has more favourable therapeutic index than aminothiol radioprotectors. (British Journal of Radiology) Zinc aspartate shown to have stronger effects on muscle power than zinc oxide. Compared to zinc gluconate zinc aspartate shown stronger effects on immune cells. Endurance athletes may develop a zinc deficiency because of dietary deficiencies and increased zinc demands and losses. Zinc supplementation also contributes to brain function, immune system, mood, appetite, cuts the common cold short, also benefits taste and smell (source: Bhowmik, D., Chiranjib, K., & Kumar, S. (2010).
Hasan Türüt, Ergul Belge Kurutas, Ertan Bulbuloglu, Alptekin Yasım, Mesut Özkaya, Ahmet Onder, Secil Simsek Imrek,
Zinc Aspartate Alleviates Lung Injury Induced by Intestinal Ischemia-Reperfusion in Rats, Journal of Surgical Research, Volume 151, Issue 1,
2009, Pages 62-67, ISSN 0022-4804, https://doi.org/10.1016/j.jss.2008.01.004.
Floersheim, G. L., & Floersheim, P. (1986). Protection against ionising radiation and synergism with thiols by zinc aspartate. The British journal of radiology, 59(702), 597-602.https://doi.org/10.1259/0007-1285-59-702-597
Floersheim, G. L., Chiodetti, N., & Bieri, A. (1988). Differential radioprotection of bone marrow and tumour cells by zinc aspartate. The British journal of radiology, 61(726), 501-508. https://doi.org/10.1259/0007-1285-61-726-501PDF/EPUB
Micheletti, A., Rossi, R., & Rufini, S. (2001). Zinc status in athletes: relation to diet and exercise. Sports medicine, 31, 577-582.
Bhowmik, D., Chiranjib, K., & Kumar, S. (2010). A potential medicinal importance of zinc in human health and chronic. Int J Pharm, 1(1), 05-11. 10.1016/j.clinbiochem.2011.08.795
B12 – methylcobalamine
B12 methylcobalamine known for increasing brain function, reduce risk of heart disease, increases energy levels, improves sleep and nerve functions. Methylcobalamine helped diabetic peripherial neuropathy patients alone and also in combination with manual acupuncture. B12 and folate improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment. B12 might help help protect against chronic diseases and neural tube defects. Symptoms of vitamin B12 deficiency included unsteadily walking in the darkness and hypopallesthesia, and some chronic diseases such as cerebral ischemia, hypertension, Parkinson’s disease (Parkinsonism), diabetes mellitus and coronary heart disease. Most of the vitamin B12 deficient patients had neuroelectricphysiological abnormalities.
Chen, W., Yang, G. Y., Liu, B., Manheimer, E., & Liu, J. P. (2013). Manual acupuncture for treatment of diabetic peripheral neuropathy: a systematic review of randomized controlled trials. PloS one, 8(9), e73764. https://doi.org/10.1371/journal.pone.0073764
Lehmann, M., Regland, B., Blennow, K., & Gottfries, C. G. (2003). Vitamin B12-B6-folate treatment improves blood-brain barrier function in patients with hyperhomocysteinaemia and mild cognitive impairment. Dementia and geriatric cognitive disorders, 16(3), 145-150. https://doi.org/10.1159/000071002
Ryan-Harshman, M., & Aldoori, W. (2008). Vitamin B12 and health. Canadian Family Physician, 54(4), 536-541. https://www.cfp.ca/content/54/4/536.short
Wang, Y. H., Yan, F., Zhang, W. B., Ye, G., Zheng, Y. Y., Zhang, X. H., & Shao, F. Y. (2009). An investigation of vitamin B12 deficiency in elderly inpatients in neurology department. Neuroscience bulletin, 25(4), 209. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5552550/
Feedback:
” A woman I treated in Spain took the Oxystim sport Formula continously. (she didn’t take any other remedies) Husband and son in the same household caught the COVID19 – She didn’t.” – a biofeedback practitioner 
“A 18 years old client who plays American football has lot of allergies and asthma and some acne. He took the Oxystim for two weeks. Then he noticed that his skin is much better and his breathing has improved while playing football…” – a biofeedback practitioner.
” I could run on the treadmill like never before it was clearly noticable in my cardio abilities” – Medical doctor, biofeedback therapist
” I finally had a complete relaxing sleep like I never had for a very long time. Amazing!” – Client
” I suffered from stomach cramps pain around my navel and I had breathing problems especially at summer time. I took the Oxystim Sport Formula. It felt like taking an early morning deep breath, also felt awareness and heat around my navel and the cramps are gone.” – Client
